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Spermatogénèse et régulation - YouTube, Spermatogenese dissertation

Spermatogenese dissertation

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La définition de spermatogenèse dans le dictionnaire est ensemble des phénomènes d'évolution cellulaire qui aboutissent à la formation des spermatozoïdes.

Fig. 10
Histological preparation of a section through a convoluted seminiferous tubule in an adult. Outside its basal lamina a layer of myofibroblasts and fibrocytes surround the tubule. The germinal epithelium lies on the tubule wall. One can recognize the spermatogonia sitting on the basal lamina.
The nuclei of the Sertoli's sustentacular cells have a rarified chromatin and the nuclei with clear nucleolus that are often oriented perpendicular to the basal lamina. The overall picture, though, is dominated by the cells occupied with spermatogenesis.

Looking at Figures and , we find that during the spermatogonial divisions, cytokinesis is not complete. Rather, the cells form a syncytium whereby each cell communicates with the others via cytoplasmic bridges about 1 μm in diameter ( Dym and Fawcett 1971 ). The successive divisions produce clones of interconnected cells, and because ions and molecules readily pass through these intercellular bridges, each cohort matures synchronously. During this time, the spermatocyte nucleus often transcribes genes whose products will be used later to form the axoneme and acrosome.

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Through the occluding junctional complexes of the Sertoli's cells a "blood/testicle" barrier is created in the tubule. This means that outside this barrier, in the tubular periphery, cells, substances and hormones from the blood have unhindered access.
On the other hand, the inner compartment of the tubule is protected by the barrier, which is selectively permeable and serves as an entry check. This is of practical importance because haploid cells in the inner part of the tubule exhibit surface antigenic properties, different from all other body cells. They must thus be kept secluded from the immune system of the organism by the "blood/testicle" barrier.

Spermatid DNA also undergoes packaging, becoming highly condensed. The DNA is first packaged with specific nuclear basic proteins, which are subsequently replaced with protamines during spermatid elongation. The resultant tightly packed chromatin is transcriptionally inactive.

Purpose. Spermatogenesis produces mature male gametes, commonly called sperm but more specifically known as spermatozoa, which are able to fertilize the counterpart ...

Like other animals, C. elegans meiosis occurs during both oogenesis and spermatogenesis, and many meiotic processes are similar in the two germ lines. However, two genes that are involved in meiosis can show specific defects during spermatogenesis.

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